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Laughter - The best
Burning Mouth Syndrome - Part 1
- Dr.Gazala Danish . United Arab Emirates
Ctip2 gene - regulates the growth of
Enamel - A finding that could change our practices
Tooth Erosion - A problem associated
also with Dysmenorrhea
Teeth And Disease - By Stethsocope
-Published in - The Argus ,Saturday 8th March 1924
Ctip2 gene regulates the growth of enamel says a new study. For
years we have been struggling to give a better replacement for the
lost enamel.But this study could possibly throw light on Stem cell ,
Enamel regeneration , treatment for Amelogenisis Imperfecta and
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Dr. Syed Nabeel
Editor of Dental Follicle & WebMaster
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Laughter - The Best Medicine :
A dentist related that he was being sued for a root canal that had
I hope you got a good fee for it!
Actually, I did not charge anything for it. It was on my golf
partner! Who is a lawyer. When asked why he would sue his friend,
the lawyer said, Its only a law suit!
Burning Mouth Syndrome - Part 1
Dr.Gazala Danish BDS . MDS
Oral Diagnostician and Radiologist
United Arab Emirates
Stomatopyrosis , Stomatodynia , Burning Mouth Disease , Oral
Dysesthesia ,Oral Galvanism , Glossodynia ,
Painful Tongue , Burning Tongue , Hot Tongue Syndrome
International Association for Study of Pain
defines glossodynia as burning pain in the tongue, which most often
involves the tip and lateral borders of glossal mucosa. Palate, lips
and sometimes other buccal mucosa and is often associated with odd
taste, dry mouth, uncomfortable bite or denture intolerance.
Burning sensation can be seen with a number of inflammatory and
ulcerative conditions of the oral mucosa, but the term “Burning
Mouth Syndrome” is reserved to a condition where there is oral
burning with no detectable cause. There are no mucosal lesions or no
known neurological disorders to explain the symptoms and there are
no characteristic laboratory findings.
The causes of burning sensation in the mouth are multifactorial and
divided into three groups; local, systemic and psychogenic.
Local factors :
The onset of symptoms, as reported by patients related to previous
dental treatment, may be as high as 65%. Conversely Nater et al.
found it was not possible to correlate any signs that implicated
dentures as a local etiologic agent. Gorsky et al. provided similar
conclusions, corroborating that denture difficulties are an
uncertain cause in the development of burning mouth syndrome.
Mucosal diseases like geographic tongue or benign migratory
Mucosal allergic reactions to allergens like methyl methacrylate
monomer, nickle sulfate, cobalt chloride and mercury. Chemicals
commonly found in denture materials were evaluated through
epicutaneous patch testing in 53 patients who wore dentures by
Kaaber et al. In this study 23% of the patients demonstrated an
allergic reaction to the substance in denture and the allergy was
determined the cause for burning sensation.
Oral allergies to food containing sorbic acid (a preservative found
in foods, ointments and creams), cinnamic aldehyde (a flavoring
agent in foods and dentifrices), nicotinic acid (used as a
rubefacient in toothpaste) and propylene glycol (a food additive)
have been reported.
A case where peanut sensitivity was a cause of burning mouth has
been reported by Burnett et al. using the serum of 10 peanut
allergic subjects, Burnett et al. identified 16 IgE-binding proteins
in a raw peanut extract and 7 IgE-binding proteins in a roasted
peanut extract by crossed radioimmunoelectrophoresis.
Dysfunction and parafunction of the stomatognathic. Parafunctional
activities resulting in excessive occlusal or denture wear has been
shown in up to 61% of studied patients with burning mouth syndrome.
Parafunctional activity of lip licking, lip sucking, lip pressure
and mouth breathing are noted in patients with perioral symptoms.
Quantity and quality
Oral salivary quantity and quality have been investigated as
causative factors in burning mouth syndrome. Irregularities in
saliva metabolites as protein, potassium and phosphate
concentrations between patients with burning mouth syndrome and
control patients have been suggested as causative factors.
systemic disease and pharmacotherapeutic agents have been shown to
diminish salivary flow rates and may be associated with increased
incidences of burning mouth syndrome symptoms.
Burning mouth symptoms may reflect a neuropathic condition possibly
involving the central or peripheral nervous system or both. Nerve
injury or dysfunction resulting from oral, facial or systemic trauma
from medical conditions might be the cause of burning sensations.
The constant burning may indicate a tonic efflux from nociceptive
primary afferents to the brain. This may be evident in inflammatory
conditions or regional nerve trauma (neuroma). Excitatory afferent
input could evoke a burning sensation with limited sensory changes
such as touch or thermal perception. Hence, the use of topical local
anesthetic in the burning oro-facial region did not interrupt the
To Be Continued -
Ctip2 gene - regulates the growth of Enamel - A finding that could
change our practices
Ctip2 plays a role in immune response, as well as
Dermatological and Nervous development was already known and its
role in enamel growth was recently found in the University Of Oregon
, where they bred mice which lacked the Ctip2 gene found that the
mice lacked Enamel.For years scientists have been trying to grow
ameloblasts. This finding may help in future for possibly
replacement of lost Enamel.This finding has laid the foundation for
the future stem cell research in Enamel growth.
Professor Chrissa Kioussi, professor of Pharmacology
, the author of the study published in the Proceedings of the
National Academy of Sciences .
Tooth Erosion - A problem associated also with Dysmenorrhea
The one etiology of the tooth erosion could be dysmenorrhea
says Journal of ADG nov/dec 2008 issue . Though bulimea was
one classical reason , vomiting resulting from dysmenorrhea
which is involuntary resulting from the contractions in the
uterus or the abdominal wall . The erosion pattern in
bulimia is restricted to the maxillary anterior teeth, as
the patient controls the direction of force whereas in
vomiting resulting from dysmenorrhea most of the teeth could
get effected. Bulimia patients are normally in their 20's
and 30's whereas the patients suffering from erosion due to
dysmenorrhea could get aware of the enamel erosion only in
their 5th or 6th decade of life.
Mohamed Bassiouny, DMD, MSc, PhD is the
author of the study.
Teeth And Disease - By Stethsocope -Published
in - The Argus ,Saturday 8th March 1924
Mouth is the mirror of health was
mostly coined later. In the above article published in 1924 - shows
the interest of the media in promoting the importance of good oral