Aligners – The Big Market

Align Technology is a medical device provider focused on malocclusion or teeth misalignment condition. Currently, around 60%–75% of the total world population is affected by this condition.

While ten million people in developed markets seek treatment from orthodontists every year, half of them suffer from mild to moderate malocclusion, which is the target market for Align Technology’s Invisalign system. Around 100 million people in the world prefer to straighten their teeth at home using clear aligner technology. This doctor-directed home market is also a major growth opportunity for Align Technology.

In 2016, the Clear Aligner segment reported revenues of close to $958.3 million, which made up 89% of the company’s total revenues. The Clear Aligner segment’s revenues are further categorized into a comprehensive product and non-comprehensive product revenues.

Comprehensive products involve Invisalign Full, Invisalign Teen, and Invisalign Assist product lines. While Invisalign Full consists of the set of aligners required by dentists, Invisalign Teen includes additional features suitable for teenage patients.

Notably, the Core S&P Mid-Cap ETF (IJH) has about 0.67% of its total portfolio holdings in Align Technology.

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Pregnancy may be blocked by a Periodontal Pathogen Porphyromonas Gingivalis

Researchers at the University of Helsinki found  delay conception in young women could be associated with P Gingivalis.

The study, published June 12 in the Journal of Oral Microbiology, included 256 healthy, non-pregnant women ranging in age from 19 to 42 from Southern Finland who had discontinued contraception in order to become pregnant.

Participants were followed for a period of 12 months to determine whether they got pregnant during that time period.

The researchers found significantly higher levels of porphyromonas gingivalis, a bacterium associated with periodontal diseases, in the saliva of women who did not become pregnant during the study period compared to those who did become pregnant.

The women with P. gingivalis in their saliva had three times more difficulty getting pregnant compared to women without the bacterium.

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Align Technology – A business built on patents

Align Technology was founded in 1997 by two Stanford MBA students, Zia Chishti and Kelsey Wirth, who had no background in orthodontics (Chishti had undergraduate degrees in economics and computer science, Wirth in literature and American History). But the pair believed that a clear version of braces would be a huge hit, upending an industry that had been using roughly the same metal brackets-and-wires to straighten teeth for decades. Believers helped them raise $130 million in a 2001 public offering, but much of that money was blown on sales and marketing efforts, including a massive national direct to consumer ad campaign. They spent $52 million that same year but only sold $45 million worth of the aligners.

After years of tepid growth, Align’s Silicon Valley tech is winning over more customers in the slow-changing orthodontics business, boosting company sales 28% year-over-year. It has an estimated 80% of the North America “clear aligner” orthodontics market, and is offered by more than 50,000 orthodontists and dentists. Invisalign hit its 4 millionth patient in September. In 2016, sales hit $1 billion for the first time. The stock is up 62% in the last 12 months, well outpacing the S&P 500, which is up 13% in the same time. Its success is due to its near monopoly on clear braces, but also its patented processes that digitally map and build out a patient’s treatment.

Now the company is reaching a crossroads and some wonder if it can continue to deliver such sparkling returns. On the one hand, there are still plenty of teeth for it to straighten. Last year Invisalign products were used in roughly 8% of the 3 million new orthodontic patients in North America. On the other hand, one of its biggest advantages – its arsenal of more than 400 U.S. and 300 foreign-issued patents covering everything from the type of plastic that’s worn in patients’ mouths to the software orthodontists use to plan out teeth movements millimeter-by-millimeter, months in advance – is facing its term limits.

global dental implants market is expected to be USD 6.81 billion by 2024

The global dental implants market is expected to be USD 6.81 billion by 2024, based on a new report by Grand View Research, Inc. Rising demand for tooth (or teeth) replacement has provided good growth potential to the market. Growing number of dental injuries owing to road accidents and sport injuries are also considered as some of the major factors favouring demand of implants.

Further Key Findings from the Study Suggest:

  • The overall market was dominated by titanium because of various applications during surgical placements: one-stage and two-stage techniques Titanium implants provide a cost-effective solution for dental implant treatments due to their long lifespan. However, titanium is prone to corrosion.
  • Zirconia implants are growing at a faster CAGR of over 8.0% over the forecast period. Introduction of zirconia implants has enhanced the outcome of dental implant treatments. It is a corrosion-free metal, which acts as an added advantage for dental implant surgeries.
  • Europe held the largest share of around USD 1.5 billion in 2015. One of the primary factors favoring this growth includes high geriatric population base. Presence of key player such as Institut Straumann AG is also expected to contribute toward the market share. Moreover, increasing number of sports related facial injuries has also led to the growing demand for oral rehabilitation, which is expected to drive the growth over the forecast period.
  • Asia Pacific is anticipated to witness the highest CAGR over the forecast period. Increasing economic stability and spending capacity are further estimated to boost market growth. Growing healthcare dispensing power in countries like Japan is expected to aid in case of high cost of dental implant procedures. Increasing base of dentists and implantologists in China is also estimated further contribute toward growth in the near future
  • Some key companies are Nobel Biocare Services AG; BioHorizons IPH, Inc.; Institut Straumann AG; Zimmer Biomet Holdings, Inc.; DENTSPLY Sirona; OSSTEM IMPLANT; Bicon, LLC; Leader Italy; Anthogyr SAS; KYOCERA Medical Corporation; DENTIUM Co., Ltd.; T-Plus Implant Tech. Co.; and DENTIS.
  • Strategic collaboration, mergers and acquisitions, and expansion of product portfolio through R&D initiatives are some of the major strategies that companies are focusing on with an aim to cater to the accentuating demand for dental implants.

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Avulsed Tooth Re-Implantation with 7 months Follow up

SIlver Amalgam Restorations raise levels of mercury in the body, UGA study says

A study has been published on deleterious effects of Dental Restorations. We would not like to write more about it than just posting two links. One, to a news website of University of Georgia and another to the abstract of science direct.

University of Georgia News

Science Direct